منابع مشابه
Hyaluronan-binding protein in endothelial cell morphogenesis
Previous studies from several laboratories have provided evidence that interaction of hyaluronan (HA) with the surface of endothelial cells may be involved in endothelial cell behavior. We have recently characterized a mAb, mAb IVd4, that recognizes and neutralizes HA-binding protein (HABP) from a wide variety of cell types from several different species (Banerjee, S. D., and B. P. Toole. 1991....
متن کاملHyaluronan is a prerequisite for ductal branching morphogenesis.
Hyaluronan, a macromolecular carbohydrate polymer of the extracellular matrix is prominent early in embryogenesis, coinciding with rapid tissue growth. CD44, the predominant receptor for hyaluronan on vertebrate cells, is a variably expressed transmembrane glycoprotein. Mouse anterior prostate glands obtained at various postnatal time points were examined for the expression of hyaluronan and CD...
متن کاملLimb morphogenesis: connections between patterning and growth
Limb development is a complex process involving precise control of both patterning and growth. Great strides have been made in understanding limb morphogenesis and identifying essential patterning genes in Drosophila. Differential expression of these genes divides the future limb into territories, which will give rise to different regions of the adult appendage. Recent analyses have defined the...
متن کاملMulti-model Simulations of Chicken Limb Morphogenesis
Early development of multicellular organisms (morphogenesis) is a complex phenomenon. We present COMPUCELL, a multi-model software framework for simulations of morphogenesis. As an example, we simulate the formation of the skeletal pattern in the avian limb bud, which requires simulations based on interactions of the genetic regulatory network with generic cellular mechanisms (cell adhesion, ha...
متن کاملGrowth Based Morphogenesis of Vertebrate Limb Bud
Many genes and their regulatory relationships are involved in developmental phenomena. However, by chemical information alone, we cannot fully understand changing organ morphologies through tissue growth because deformation and growth of the organ are essentially mechanical processes. Here, we develop a mathematical model to describe the change of organ morphologies through cell proliferation. ...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2007
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2007.02.023